BSE causes progressive degeneration of the nervous system in cattle resulting in changes in temperament, such as nervousness or aggression; abnormal posture; lack of coordination and difficulty in rising; decreased milk production; or loss of body weight despite continued appetite. Early in the clinical course of the disease, symptoms may be slight, undetectable or unrecognizable. Not all affected cattle display all signs of the disease.

To assist in the recognition of clinical signs at all stages, the Veterinary Laboratories Agency in the U.K., one of four OIE Reference Laboratories, has placed video clips on its Web site that can be accessed by the general public to increase awareness around the world. 

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